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Reactome | Drug resistance of KIT mutants
Reactome | Drug resistance of KIT mutants

Loss of PI3 kinase association improves the sensitivity of secondary  mutation of KIT to Imatinib | Cell & Bioscience | Full Text
Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib | Cell & Bioscience | Full Text

Current Oncology | Free Full-Text | Precision Oncology in Gastrointestinal  Stromal Tumors
Current Oncology | Free Full-Text | Precision Oncology in Gastrointestinal Stromal Tumors

Mechanisms of Disease Persistence in Gastrointestinal Stromal Tumors - The  Life Raft Group
Mechanisms of Disease Persistence in Gastrointestinal Stromal Tumors - The Life Raft Group

The role of small molecule Kit protein-tyrosine kinase inhibitors in the  treatment of neoplastic disorders - ScienceDirect
The role of small molecule Kit protein-tyrosine kinase inhibitors in the treatment of neoplastic disorders - ScienceDirect

Current and emerging strategies for the management of imatinib-refractory  advanced gastrointestinal stromal tumors - Damien Kee, John R. Zalcberg,  2012
Current and emerging strategies for the management of imatinib-refractory advanced gastrointestinal stromal tumors - Damien Kee, John R. Zalcberg, 2012

Diapositiva 1
Diapositiva 1

GIST Mutations - Types of GIST Cancer Gene Mutations & Testing | The Life  Raft Group
GIST Mutations - Types of GIST Cancer Gene Mutations & Testing | The Life Raft Group

IJMS | Free Full-Text | Mutated KIT Tyrosine Kinase as a Novel Molecular  Target in Acute Myeloid Leukemia
IJMS | Free Full-Text | Mutated KIT Tyrosine Kinase as a Novel Molecular Target in Acute Myeloid Leukemia

PDF] The SCF/c-KIT system and imatinib actions in prostate cancer: a  cross-talk with RGN? | Semantic Scholar
PDF] The SCF/c-KIT system and imatinib actions in prostate cancer: a cross-talk with RGN? | Semantic Scholar

KIT kinase mutants show unique mechanisms of drug resistance to imatinib  and sunitinib in gastrointestinal stromal tumor patients | PNAS
KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients | PNAS

Genetic progression in gastrointestinal stromal tumors: mechanisms and  molecular interventions. - Abstract - Europe PMC
Genetic progression in gastrointestinal stromal tumors: mechanisms and molecular interventions. - Abstract - Europe PMC

Ripretinib in advanced gastrointestinal stromal tumors: an overview of  current evidence and drug approval | Future Oncology
Ripretinib in advanced gastrointestinal stromal tumors: an overview of current evidence and drug approval | Future Oncology

The KIT receptor tyrosine kinase. (A) C-KIT mutations occur in 80 –90%... |  Download Scientific Diagram
The KIT receptor tyrosine kinase. (A) C-KIT mutations occur in 80 –90%... | Download Scientific Diagram

Using Imatinib for Adjuvant Treatment after Resection of Kit-positive GIST  - The ASCO Post
Using Imatinib for Adjuvant Treatment after Resection of Kit-positive GIST - The ASCO Post

JCI - Structural reengineering of imatinib to decrease cardiac risk in  cancer therapy
JCI - Structural reengineering of imatinib to decrease cardiac risk in cancer therapy

Presentazione standard di PowerPoint
Presentazione standard di PowerPoint

Frontiers | An overview of agents and treatments for PDGFRA-mutated  gastrointestinal stromal tumors
Frontiers | An overview of agents and treatments for PDGFRA-mutated gastrointestinal stromal tumors

c-KIT and PDGFRA mutation detection for GIST – آزمایشگاه پرتولب
c-KIT and PDGFRA mutation detection for GIST – آزمایشگاه پرتولب

Complementary activity of tyrosine kinase inhibitors against secondary kit  mutations in imatinib-resistant gastrointestinal stromal tumours | British  Journal of Cancer
Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours | British Journal of Cancer

Spectrum of activity of dasatinib against mutant KIT kinases associated  with drug-sensitive and drug-resistant gastrointestinal stromal tumors |  SpringerLink
Spectrum of activity of dasatinib against mutant KIT kinases associated with drug-sensitive and drug-resistant gastrointestinal stromal tumors | SpringerLink

Clinicopathological significance of c-KIT mutation in gastrointestinal  stromal tumors: a systematic review and meta-analysis | Scientific Reports
Clinicopathological significance of c-KIT mutation in gastrointestinal stromal tumors: a systematic review and meta-analysis | Scientific Reports

Imatinib Mesylate — A New Oral Targeted Therapy | NEJM
Imatinib Mesylate — A New Oral Targeted Therapy | NEJM

Encapsulation of Imatinib in Targeted KIT-5 Nanoparticles for Reducing its  Cardiotoxicity and Hepatotoxicity | Bentham Science
Encapsulation of Imatinib in Targeted KIT-5 Nanoparticles for Reducing its Cardiotoxicity and Hepatotoxicity | Bentham Science

Acquired resistance to imatinib in gastrointestinal stromal tumours caused  by multiple KIT mutations - The Lancet Oncology
Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations - The Lancet Oncology

Efficacy of SCF drug conjugate targeting c-KIT in gastrointestinal stromal  tumor | BMC Medicine | Full Text
Efficacy of SCF drug conjugate targeting c-KIT in gastrointestinal stromal tumor | BMC Medicine | Full Text